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KMID : 0388320020090010113
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Journal of Korean Academy of Fundamental Nursing
2002 Volume.9 No. 1 p.113 ~ p.122
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A Study on Serum Ferrum, TIBC, and Ferritin´s Circadian Rhythm in Normal Adults
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Jeong Suk-Heui
Kim Myung-Ae
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Abstract
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Purpose: The purpose of this study was to identify characteristics of serum ferrum, TIBC and ferritin´s circadian rhythm in normal adults and to prepare a standard to determine the examination material extraction time.
Methods:Nine women and ten men made up the convenience sample for this study. They were from the´staff of D university hospital and students in D medical School located in K city who met the qualifications for inclusion in the sample. The value of serum ferrum, TIBC and circadian rhythm were calculated as follows: First, each variable´s amplitude, the acrophase and average were measured for a 24 hour cycle using the cosinor method, and then each person´s rhythm was analyzed.
Results: There were significant serum iron circadian rhythm for both men. And women (p<.05). For the men, mesor was 105.91ug/dh, amplitude was 29.52ug/de, and the acrophase was 9.76 hour. For the women. Mesor was 108.17gg/de, amplitude was 28.09gg/di, and the acrophase was 11.42 hour. The rhythm change of TIBC was only significant for the women (p(.05), mesor was 383.39mg/dtf, amplitude was 60.29 mg/d, and the acrophase was 14.93hour. As for the circadian rhythm of the ferritin, there are no diurnal variation in either sex, men were between 134.Ong/mt and 137.4ng/ mC, and women, between 29.1ng,/mf and 30.ing/mf.
Conclusion: To help diagnose the boundary line between normal or deficiency in iron, measurement should be carried out at a fixed time in the morning and evening, or a more proper time would be in the afternoon at the time when the width of amplitude is the least.
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KEYWORD
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Circadian Rhythm, Serum Total Iron-Binding Capacit, Ferritin, Serum Iron Level
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